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New drug may provide significant benefits to brain injury survivors and stroke victims, even years after an injury occurs

A new study in the journal, CNS Drugs reports that a drug, etanercept, seems to provide clinical improvement to brain injury survivors and stroke survivors, even years after the stroke or traumatic event by reducing brain inflamation.

The study of 629 patients, conducted over the course of nearly two years, documents a diverse range of positive effects, including statistically significant rapid clinical improvement in motor impairment, spasticity, cognition, etc. in the stroke group, with a similar pattern of improvement seen in the traumatic brain injury (TBI) group. The study involved 617 patients treated an average of 42 months after stroke and 12 patients treated an average of 115 months after TBI, long after further spontaneous meaningful recovery would be expected.

Here is the full citation to the study: Tobinick E, Kim N, Reyzin G, et al. Selective TNF Inhibition for Chronic Stroke and Traumatic Brain Injury – An Observational Study Involving 629 Consecutive Patients Treated with Perispinal Etanercept. CNS Drugs, 2012; 16 (12)




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